next-dental

egypt

Egypt.

Teebone is an osteoconductive alloplastic material designed for bone substitution. Its biphasic nature allows a controlled resorption profile similar to human bone. Due to its composition, 75% Hydroxiapatite and 25% Beta tricalcium phosphate, Teebone regenerates new bone through two different stages of activation. The breakdown of B-TCP by the osteoclast will free ions that enhance bone grow, while the hydroxyapatite acts as support for the bone ingrown whiting the graft, being slowly substituted.
<h6>Indications</h6>
<img src="https://static.wixstatic.com/media/8b9816_21a5798d82fa4ca8b3f92f3d913d1d1e~mv2.jpg/v1/fill/w_630,h_185,al_c,q_80,usm_0.66_1.00_0.01,enc_auto/tc1%20-%20Copy.jpg" alt="tc1 - Copy.jpg" style="margin: 0px; padding: 0px; outline: 0px; vertical-align: baseline; background: transparent; object-position: 50% 50%; filter: var(--filter-effect-svg-url); -webkit-mask-image: var(--mask-image,none); -webkit-mask-position: var(--mask-position,0); -webkit-mask-size: var(--mask-size,100% 100%); -webkit-mask-repeat: var(--mask-repeat,no-repeat); position: static; box-shadow: rgb(0, 0, 0) 0px 0px 0px; user-select: none; width: 630px; height: 185px; object-fit: cover;">
<h5>Key Features & Benefits</h5>
<img src="https://static.wixstatic.com/media/8b9816_0cd53ff55d3846af972713580ff24073~mv2.png/v1/fill/w_153,h_100,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/1_2.png" alt="1.2.png" style="margin: 0px; padding: 0px; outline: 0px; vertical-align: baseline; background: transparent; object-position: 50% 50%; filter: var(--filter-effect-svg-url); -webkit-mask-image: var(--mask-image,none); -webkit-mask-position: var(--mask-position,0); -webkit-mask-size: var(--mask-size,100% 100%); -webkit-mask-repeat: var(--mask-repeat,no-repeat); position: static; box-shadow: rgb(0, 0, 0) 0px 0px 0px; user-select: none; width: 153px; height: 100px; object-fit: cover;">
<h6>No Membrane</h6>
It is not necessary to use membrane, due to its physical and mechanical properties.
<img src="https://static.wixstatic.com/media/8b9816_bad74339cc9743ffbc7bfccfa7ed0577~mv2.png/v1/crop/x_0,y_0,w_494,h_326/fill/w_151,h_100,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/1_5.png" alt="1.5.png" style="margin: 0px; padding: 0px; outline: 0px; vertical-align: baseline; background: transparent; object-position: 50% 50%; filter: var(--filter-effect-svg-url); -webkit-mask-image: var(--mask-image,none); -webkit-mask-position: var(--mask-position,0); -webkit-mask-size: var(--mask-size,100% 100%); -webkit-mask-repeat: var(--mask-repeat,no-repeat); position: static; box-shadow: rgb(0, 0, 0) 0px 0px 0px; user-select: none; width: 151px; height: 100px; object-fit: cover;">
<h6>Security</h6>
100% synthetic and 100% resorbable
<img src="https://static.wixstatic.com/media/8b9816_54e80512c9f146d6aaf23c377410450f~mv2.png/v1/crop/x_0,y_0,w_491,h_326/fill/w_150,h_100,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/1_4.png" alt="1.4.png" style="margin: 0px; padding: 0px; outline: 0px; vertical-align: baseline; background: transparent; object-position: 50% 50%; filter: var(--filter-effect-svg-url); -webkit-mask-image: var(--mask-image,none); -webkit-mask-position: var(--mask-position,0); -webkit-mask-size: var(--mask-size,100% 100%); -webkit-mask-repeat: var(--mask-repeat,no-repeat); position: static; box-shadow: rgb(0, 0, 0) 0px 0px 0px; user-select: none; width: 150px; height: 100px; object-fit: cover;">
<h6>Easy Handling</h6>
teebone® is very hydrophilic which confers an excellent cohesivity between the particles.
<img src="https://static.wixstatic.com/media/8b9816_18f288c0076546dab93854a2042f5b80~mv2.png/v1/fill/w_154,h_94,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/1_6.png" alt="1.6.png" style="margin: 0px; padding: 0px; outline: 0px; vertical-align: baseline; background: transparent; object-position: 50% 50%; filter: var(--filter-effect-svg-url); -webkit-mask-image: var(--mask-image,none); -webkit-mask-position: var(--mask-position,0); -webkit-mask-size: var(--mask-size,100% 100%); -webkit-mask-repeat: var(--mask-repeat,no-repeat); position: static; box-shadow: rgb(0, 0, 0) 0px 0px 0px; user-select: none; width: 154px; height: 94px; object-fit: cover;">
<h6>Vascularisation</h6>
teebone® induces a remarkable vascularisation.
<img src="https://static.wixstatic.com/media/8b9816_4ae19c09c2b942bfaa39d99774e60122~mv2.png/v1/fill/w_154,h_100,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/1_3.png" alt="1.3.png" style="margin: 0px; padding: 0px; outline: 0px; vertical-align: baseline; background: transparent; object-position: 50% 50%; filter: var(--filter-effect-svg-url); -webkit-mask-image: var(--mask-image,none); -webkit-mask-position: var(--mask-position,0); -webkit-mask-size: var(--mask-size,100% 100%); -webkit-mask-repeat: var(--mask-repeat,no-repeat); position: static; box-shadow: rgb(0, 0, 0) 0px 0px 0px; user-select: none; width: 154px; height: 100px; object-fit: cover;">
<h6>Total Resorption</h6>
teebone® is replaced by new vital bone within 6 -24 months.
<img src="https://static.wixstatic.com/media/8b9816_64ce0e79a2d7401c81630fc005ddc8fb~mv2.png/v1/fill/w_154,h_94,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/1_7.png" alt="1.7.png" style="margin: 0px; padding: 0px; outline: 0px; vertical-align: baseline; background: transparent; object-position: 50% 50%; filter: var(--filter-effect-svg-url); -webkit-mask-image: var(--mask-image,none); -webkit-mask-position: var(--mask-position,0); -webkit-mask-size: var(--mask-size,100% 100%); -webkit-mask-repeat: var(--mask-repeat,no-repeat); position: static; box-shadow: rgb(0, 0, 0) 0px 0px 0px; user-select: none; width: 154px; height: 94px; object-fit: cover;">
<h6>Radiopaques</h6>
Allows the perfect monitorization of osteointegration.
<img src="https://static.wixstatic.com/media/8b9816_e8cfc96b1e9345c3a9922df2b3525440~mv2.jpg/v1/fill/w_979,h_290,al_c,q_80,usm_0.66_1.00_0.01,enc_auto/tc2%20-%20Copy.jpg" alt="tc2 - Copy.jpg">
 

<h5>Device Description</h5>
teebone® BCP is a synthetic macroporous ceramic, containing hydroxyapatite and beta tricalcium phosphate, that does not incorporate a medical substance, nor tissues or blood products. The porous synthetic ceramic, containing beta tricalcium phosphate has been widely studied in the market and is not new. teebone® BCP is a sterile, single use, product that is gamma ray radiated using 25kGy. The macroporous ceramic allows an excellent osseointegration, as well as a total vascularization of the implant due to the interconnected porosity. teebone® BCP is designed for the filling of bone voids or defects of the skeletal system, replacing the bone structure gap. Due to the interconnected porosity of teebone® BCP, the implant can be total vascularized which allows an excellent osseointegration. New bone formation will occur and slowly replace the porosity of the implant, and the implant itself.
<h5>Intended Use</h5>
teebone® BCP, is a porous synthetic ceramic, designed for the filling of bone voids or defects of the skeletal system that are not intrinsic to the stability of the bony structure.
<h5>Mechanism of Action</h5>
According to the size and geometry of the bone defect, the surgeon establishes the appropriate dosage form to be applied. Irregular bone defects can be filled with granules or combinations of granules, blocks and cylinders.

Bone defects with defined geometric shape can be filled with blocks and cylinders.
Before implantation, teebone® BCP should be impregnated with patient’s blood or autologous bone marrow, in order to introduce blood cells, growth factors and, in case of bone marrow , osseoprogenitor cells into the graft.

After the impregnation step, the device should be immediately placed into the bone defect, in contact with cancellous tissue. The bone surface must be freshened and slightly bleeding to ensure an appropriate supply of blood cells and growth factors to the entire graft material.

The filling of the bone defect must be completed with a slight impaction and the wound closure must be complete and airtight.
The combination of teebone® BCP with any medical substance during implantation is carried out under the surgeon’s responsibility.
<h5>Precautions</h5>
As with any surgical procedure, care should be exercised in treating individuals with preexisting conditions that may affect the success of the surgical procedure. This includes individuals with bleeding disorders of any etiology, long-term steroidal therapy, immunosuppressive therapy, or high dosage radiation therapy.

Avoid overfilling the bone defect site or attempt to pressurize the treatment site.

teebone® BCP&nbsp; should not be used at infected sites.

teebone® BCP is not intended for load-bearing uses. It is important to ensure that the area where the teebone® BCP have been implanted be properly secured mechanically with rigid fixations to strengthen the surroundings.

Attempts should not be made to modify the size of the granules or to change their shape. Experienced users may, if required adapt the cylinders or blocks to the defect by careful mechanical reworking prior to implantation, without compromising their function (e.g. pronounced comminution, cutting). Machining the cylinders or block should be performed with them hydrated (e.g. blood or saline solution), and NOT performed in situ to prevent ceramic dust entering the wound bed, which would induce macrophage activity in the form of inflammatory reaction. The dust resulting from this procedure must be carefully removed before inserting the implant.

teebone® BCP must be properly secured to prevent potential migration and should only be used in surgical procedures where bone grafts substitutes are adequately contained.&nbsp;
<h5>Composition</h5>
teebone® BCP consists of 75% of&nbsp; hydroxyapatite and 25% of β-TCP and comply with ISO 13779-1:2008 – Implants for surgery – Hydroxyapatite – Part 1: Ceramic hydroxyapatite.

Table –&nbsp;teebone® BCP composition.
<h5>Compound</h5>
<h5>Synonyms</h5>
<h5>Formula</h5>
<h5>CAS Number</h5>
<h5>Supplier</h5>
Beta-Tricalcium Phosphate
Hydroxyapatite
Tricalcium diphosphate
Calcium hydroxyapatite
β-Ca3(PO4)2
Ca5(PO4)3(OH)
7758-87-4
12167-74-7
Himed
Himed
<h5>Control of Raw Materials</h5>
All lots of raw materials used in the production of teebone® BCP are fully traceable. The control of raw material is performed according to the following processes:

<ol><li>Incoming Inspection</li></ol>
<ul><li>All received raw materials and production materials are identified inspected and labeled by qualified personnel according to applicable procedures.</li><li>The CoC and/or CoA and/or MDS documents, which are obligatory provided by the suppliers are verified and properly maintained.</li><li>The incoming inspection results are documented, and the records are filed as quality records.</li><li>The materials are issued for use in the process only after this inspection and approval.</li></ul>
&nbsp; &nbsp;2.Traceability
<ul><li>The Company maintains traceability of all lots of raw materials used.</li><li>All materials and products in all manufacturing process stages are identified and labeled</li><li>The identification of the products, together with the data and information collected on manufacturing inspection and testing enable full traceability on the product.</li><li>The Company maintains traceability of lots of products manufactured.</li><li>This system ensures full information concerning products in case of non-conformities, complaints, returned products or any other reason.</li></ul>
<h5>Sterilization Method</h5>
teebone® BCP is sterilized by gamma radiation at Synergy Helath, now part of STERIS, at the Reading Facility site (Marcus Close Reading Berkshire RG30 4EA United Kingdom). The Synergy Health firm is certified by the means of the system ISO 9001 / EN ISO 13485 by the BSI certifying body firm and is registered FDA facility nº 3002807310.
<h5>Sterilization Validation</h5>
The sterilization method was validated according to EN ISO 11137-1:2006 “Sterilization of health care products – Radiation – Part 1: Requirements for development, validation and routine control of a sterilization process for medical devices”, EN ISO 11137-2:2013 “Sterilization of health care products – Radiation – Part 2 : Establishing the sterilization dose, EN ISO 11737-1:2006 “Sterilization of medical devices – Microbiological methods – Part 1: Determination of a population of microorganisms on products” and EN ISO 11737-2:2009 “Sterilization of medical devices – Microbiological methods – Part 2: Tests of sterility performed in the definition, validation and maintenance of a sterilization process”.

The validation of the sterilization method of teebone® BCP included: maximum dose compatibility test, VDmax method and dose mapping.
<h5>Packaging Validation</h5>
In the packaging system of granules, the sterile barrier is constituted by the pouch. The sterile barrier of the packaging system of the preform shapes is constituted by the blister.
<h5>Biocompatibility</h5>
The use of hydroxyapatite and β-Tricalcium phosphate&nbsp;in vivo&nbsp;is well known and has been studied and evaluated in numerous animal and human studies over the years. Furthermore, teebone® BCP has been manufactured and distributed in the European market for 7 years without any adverse event to report up to date. The performance of teebone® BCP in the areas of intended uses, have proven that the material is non-toxic, biocompatible, resorbable and gradually replaced by new bone while in contact with vital bone.

Medibrex Teebone Biphasic Bone Graft

Colla-DM is purified bovine collagen type I derived from bovine of BSE free zone authorized by OIE.&nbsp;
Product Features:
1) Adhesive property & Flexibility
- Easy manipulation and placement
- High hydrophilic property and excellent flexibility
2) Multiple-Layered Structure
- Effective bone & tissue regeneration by securing enough space maintenance
- Facilitating proliferation of osteoblasts
3) Safety:
- Derived from bovine of BSE (Bovine Spongiform Encephalopathy) Free zone authorized by OIE (Office International Des Epizooties)
Resorbtion Period: 3-6 months
Indications: Sinus Lift / Ridge augmentation / Fenestration defects / Horizontal augmentation / Alveolar ridge reconstruction / Dehiscence
 
Resorbable collagen membrane having both&nbsp;advantages of soft and hard type
<img src="https://www.bdh.co.th/images/editor/Colla-DM-%E0%B8%9A%E0%B8%97%E0%B8%84%E0%B8%A7%E0%B8%B2%E0%B8%A1.jpg" alt="Medpark Colla-DM Resorbable Collagen Membrane Implant Brand Bone Graft Brand Bone Graft for Implant regenerative materials and dentistry Best Bone Graft วัสดุปลูกกระดูกสำหรับงานรากเทียม / วัสดุปลูกกระดูกคุณภาพสูง / แนะนำวัสดุปลูกกระดูก / แนะนำ Bone graft / ผู้แทนจำหน่าย Bone Graft / Bone Graft ในประเทศไทย /BDH Medical Supply /บีดีเอชเมดิคอล ซัพพลาย / bone graft dealer / บริษัทรากเทียม ">
<table><tbody><tr><td>Adhesive Property & Flexibility</td><td>· Easy manipulation and placement
· High hydrophilic property and excellent flexibility</td></tr><tr><td>Multiple-Layered Structure</td><td>· Effective bone & tissue regeneration&nbsp;by securing enough space maintenance
· Facilitating proliferation of osteoblasts</td></tr><tr><td>Safety</td><td>· Using purified bovine collagen type I
· Derived from bovine of BSE free zone authorized by OIE</td></tr></tbody></table>

Colla-DM is purified bovine collagen type I derived from bovine of BSE free zone authorized by OIE. 

Product Features:

1) Adhesive property & Flexibility

- Easy manipulation and placement

- High hydrophilic property and excellent flexibility

Medpark Colla-D  (Resorbable Collagen Membrane)

Assuming that the clinical requirements for a barrier membrane are satisfied, individual preferences for the handling properties play a major role in the choice of collagen membranes. The easy handling of naturesQue&nbsp;ColTect P&nbsp;enables diverse applications in therapeutic concepts that include the use of regenerative measures.
<h4>Structure, design, and stability</h4>
<figure><a href="https://www.bego.com/fileadmin/user_upload/Images_Contents/Implants/Biomaterialien/naturesQues/BIS_naturesQues_ColTect-P_5_Membran_300x_gekippt-45.jpg" class="lightbox" rel="lightbox[4195]"><img class="image-embed-item" src="https://www.bego.com/fileadmin/_processed_/d/2/csm_BIS_naturesQues_ColTect-P_5_Membran_300x_gekippt-45_35c4c02e98.jpg" width="320" height="213" style="width: auto; display: block;"></a><figcaption>Scanning electron microscopy image of
naturesQue&nbsp;ColTect P.</figcaption></figure>
naturesQue&nbsp;ColTect P&nbsp;is manufactured from purified collagen-rich tissue. Using a gentle method, the collagen is minimally crosslinked to give the membrane a predictable resorption profile with maximum tissue tolerability. A crosslinked structure prevents premature enzymatic cleavage of the collagen fibers and gives
naturesQue&nbsp;ColTect P&nbsp;a reproducible and reliable barrier function that is adapted to the time profile of bone healing.
This produces a highly versatile and strong membrane with comfortable handling properties.
naturesQue&nbsp;ColTect P&nbsp;is made up of a layer of intact collagen fibers. The membrane is not side specific.
<h4>Requirements profile for a collagen membrane</h4>
Collagen membranes alone do not have sufficient mechanical stability to shape and protect defect contours. For this reason naturesQue&nbsp;ColTect P&nbsp;is used together with bone substitute materials such as naturesQue&nbsp;SemOss B&nbsp;or naturesQue&nbsp;MaxOss P.
The use of bone substitute materials creates a volumizing framework in the defect space that is used by the osteoblasts as a substrate for bone deposition.
A barrier membrane protects the spaces in the bone defect and prevents the ingrowth of soft tissues. The job of the membrane is to establish and maintain a barrier that is permeable to nutrients between the bone and soft tissue. The membrane also stabilizes the augmentation material by covering the bone defect. The barrier function of naturesQue&nbsp;ColTect P&nbsp;lasts about 3 months, which is sufficiently long to ensure adequate bone healing.
<figure><a href="https://www.bego.com/fileadmin/user_upload/Images_Contents/Implants/Biomaterialien/naturesQues/BIS_naturesQues_ColTect_P_pur_flex_forceps.jpg" class="lightbox" rel="lightbox[4195]"><img class="image-embed-item" src="https://www.bego.com/fileadmin/_processed_/0/0/csm_BIS_naturesQues_ColTect_P_pur_flex_forceps_41c38bcfa8.jpg" width="320" height="213" style="width: auto; display: block;"></a></figure>
<figure><a href="https://www.bego.com/fileadmin/user_upload/Images_Contents/Implants/Biomaterialien/naturesQues/BIS_naturesQues_ColTect-P_PosteriorFigureC_HiRes_V2.jpg" class="lightbox" rel="lightbox[4195]"><img class="image-embed-item" src="https://www.bego.com/fileadmin/_processed_/6/a/csm_BIS_naturesQues_ColTect-P_PosteriorFigureC_HiRes_V2_9cc44828f8.jpg" width="320" height="213" style="width: auto; display: block;"></a></figure>
<figure><a href="https://www.bego.com/fileadmin/user_upload/Images_Contents/Implants/Biomaterialien/naturesQues/BIS_naturesQues_ColTect_P_pur_forceps_01.jpg" class="lightbox" rel="lightbox[4195]"><img class="image-embed-item" src="https://www.bego.com/fileadmin/_processed_/4/c/csm_BIS_naturesQues_ColTect_P_pur_forceps_01_d6c7940d97.jpg" width="320" height="213" style="width: auto; display: block;"></a></figure>
<h4>Handling and feel</h4>
<figure><a href="https://www.bego.com/fileadmin/user_upload/Images_Contents/Implants/Biomaterialien/naturesQues/BIS_naturesQues_ColTect-P_Hand-Hapt_1.png" class="lightbox" rel="lightbox[4195]"><img class="image-embed-item" src="https://www.bego.com/fileadmin/_processed_/f/2/csm_BIS_naturesQues_ColTect-P_Hand-Hapt_1_a1d5b1f9f2.png" width="200" height="141" style="width: auto; display: block;"></a></figure>
<figure><a href="https://www.bego.com/fileadmin/user_upload/Images_Contents/Implants/Biomaterialien/naturesQues/BIS_naturesQues_ColTect-P_Hand-Hapt_2.png" class="lightbox" rel="lightbox[4195]"><img class="image-embed-item" src="https://www.bego.com/fileadmin/_processed_/5/f/csm_BIS_naturesQues_ColTect-P_Hand-Hapt_2_61facd2fc2.png" width="200" height="141" style="width: auto; display: block;"></a></figure>
The naturesQue&nbsp;ColTect P&nbsp;membrane can be applied wet or dry. The membrane is cut to size so that the piece overlaps the margin of the defect by about 2 mm. When dry, naturesQue&nbsp;ColTect P&nbsp;is a sturdy, stable membrane. Wetting the membrane with saline or blood makes naturesQue&nbsp;ColTect P&nbsp;flexible, enabling it to be adapted to the defect contours.
It is not usually necessary to fix naturesQue&nbsp;ColTect P&nbsp;because the membrane can be easily wetted and adheres to the bone walls. Nevertheless, naturesQue&nbsp;ColTect P&nbsp;can be repositioned should this be necessary. If needed, naturesQue&nbsp;ColTect P&nbsp;can be sutured or fixed with pins.
<h4>naturesQue&nbsp;ColTect P&nbsp;put into context</h4>
Origin
<ul><li>Porcine peritoneum</li></ul>
Composition
<ul><li>Intact collagen fibers</li><li>Stabilized by reliable minimal crosslinking</li></ul>
Processing
<ul><li>Collagen-rich peritoneum</li><li>Cleaning and removal of non-collagenous proteins</li><li>Stabilization of the collagen fibers using minimal crosslinking</li><li>Washing, rinsing, and drying</li><li>Measurement, packaging, and sterilization</li><li>Quality Control</li></ul>
Application
<ul><li>Remove with sterile instruments</li><li>Processed wet or dry</li><li>Adapt to the size of the defect, overlapping by about 2 mm</li><li>Closed healing is recommended</li><li>No specific side for positioning</li><li>Can be repositioned</li></ul>
Consistency/Feel
<ul><li>Dry: Stable and rigid, sturdy</li><li>Wet: Can be draped, sturdy, adhesive, not sticky</li><li>Does not stretch</li><li>Tear resistant</li></ul>
Resorption
<ul><li>Resorption time between 12 and 16 weeks</li></ul>

Assuming that the clinical requirements for a barrier membrane are satisfied, individual preferences for the handling properties play a major role in the choice of collagen membranes. The easy handling of naturesQue ColTect P enables diverse applications 

Bego NaturesQue ColTect P ( Xenogeneic porcine barrier membrane )

<h1>SHELTER</h1>
SHELTER is a pericardium membrane of bovine origin and, thanks to the innovative Pericross decellularization system, the three-dimensional structure of collagen is maintained.
The multidirectional composition of the pericardial collagen fibers allows for greater stability and protection to the graft site.
At UBGEN we have developed two types of membranes:
<ul><li>SHELTER Fast, a membrane with a fast resorption time (4-5 weeks) thanks to the particular broad-textured collagen structure;</li><li>SHELTER Slow, a membrane with a slower resorption time (3-6 months) due to a modified three-dimensional structure of collagen fibres, that are more resistant because of intensified bonds.</li></ul>
SHELTER Fast and SHELTER Slow are occlusive to the passage of cells. They are designed to promote osteoblastic and periodontal ligament cells proliferation, protecting the site from soft tissue colonization; stable and resistant to traction they are easy and manageable in positioning.
<h2>&nbsp;Why to choose SHELTER</h2>
<ol><li>Optimal clinical handling: Shelter adapts perfectly to the contours of the defect, does not stick to gloves or instruments;</li><li>The multilayer structure makes it elastic and flexible;</li><li>It can be used on both sides indifferently;</li><li>It is particularly resistant to traction: it accepts a wide range of sutures and fastening systems;</li><li>Supports neoangiogenesis;</li><li>It has chemotactic capacity, the tissues heal quickly in case of post-op dehiscence;</li><li>It has controlled resorption times.</li></ol>
<h2>Biocompatibility</h2>
<img src="https://www.ubgen.com/templates/yootheme/cache/Grafico_SHELTER_C-4c17408d.png" alt="Tabella 1"> 
 
 Table 1&nbsp;- The cross-linking process of the Slow membrane allows the latter to be reabsorbed in a longer period of time (3-6 months) than the Fast; this is due to the greater number of intramolecular bonds between the collagen fibrils which confers a certain porosity after dehydration.
<figure><a href="https://www.ubgen.com/en/ubgen-solution/shelter-membranes.html#js-fb2" class="el-link" uk-toggle=""><img class="el-image" data-src="/templates/yootheme/cache/Grafico_SHELTER_D-d72d6fba.png" data-srcset="/templates/yootheme/cache/Grafico_SHELTER_D-f2ba122a.png 768w, /templates/yootheme/cache/Grafico_SHELTER_D-fa981dcf.png 1024w, /templates/yootheme/cache/Grafico_SHELTER_D-d72d6fba.png 1100w" data-sizes="(min-width: 1100px) 1100px" data-width="1100" data-height="600" uk-img="" src="https://www.ubgen.com/templates/yootheme/cache/Grafico_SHELTER_D-d72d6fba.png" sizes="(min-width: 1100px) 1100px" srcset="/templates/yootheme/cache/Grafico_SHELTER_D-f2ba122a.png 768w, /templates/yootheme/cache/Grafico_SHELTER_D-fa981dcf.png 1024w, /templates/yootheme/cache/Grafico_SHELTER_D-d72d6fba.png 1100w"></a></figure>
<img src="https://dentacarts.com/images/Grafico_SHELTER_D-d72d6fba.png?1653299970278"> 
 Table 2&nbsp;- The stress-strain curves show a characteristic trend of collagenic materials and this confirms the fact that UBGEN production processes keep the structure of the collagen fibrils and other components such as elastin intact.
COMPUTERIZED MICROTOMOGRAPHY SHELTER MEMBRANE 
The mechanical traction tests confirm that the Pericross production process maintains the exceptional resistance qualities of the intertwined collagen fibers and guarantees the natural three-dimensional structure of the material together with the chemotactic ability to attract fibroblasts.
<h1>SHELTER FAST</h1>
SHELTER Fast is the bovine pericardium membrane capable of resorbing quickly, 4-5 weeks.
<h1>Surgical applications</h1>
The following surgical applications refer to both SHELTER FAST and SHELTER SLOW.
<img src="https://dentacarts.com/images/indc%201.PNG?1653300023813">
<img src="https://dentacarts.com/images/indc%202.PNG?1653300095166">

Ubgen Shelter membrane S

dc.com

&nbsp;Crystal &mdash;oss is a natural hydroxyapatite , the bioactive bone is made from bovine source , the bovine origin is free from bovine spongiform encephalopathy (BSE)
&nbsp; Composition&nbsp; 100% hydroxyapatite cal0 (po4)6 oh2 of bovine origin in the form of granules of two different grain size (200-1000M), (1000-2000M)&nbsp;
 Advantages:&nbsp; • Interconnecting porosity and interconnected structures of the granules enable ingrowth of the bone over complete osteon structures • Osteoconductive: crystal &mdash; oss act as the scaffold for bone regeneration • Complete resorption and biocompatible crystal-oss exhibited excellent integration in the natural bone without encapsulation of connective tissue (osteotropism) • No risk of infection :crystal &mdash; oss is absolutely no risk of transmitting pathogens or risk of rejection with synthetic materials&nbsp;
 Indications:&nbsp; • socket preservation • ridge augmentation • dental implantology • periosurgery • Reconstruction of bone defects following excision pf benign tumors and crystals. • Sinus lifting • Defects following removal of autogenous bone in orthopedic surgery and craniofacial surgery&nbsp;

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 Crystal —oss is a natural hydroxyapatite , the bioactive bone is made from bovine source , the bovine origin is free from bovine spongiform encephalopathy (BSE)

 
Composition 
100% hydroxyapatite cal0 (po4)6 oh2 of bovine origin in the form of 